BY Carson Choate, The Western JournalJanuary 23, 2023
1 year ago
BY 
 | January 23, 2023
1 year ago

Moderna Begins Administering New MRNA Shot That Is Injected Directly Into the Heart

Moderna is currently developing an mRNA shot that aims to help the body produce relaxin, a hormone that can increase blood flow and potentially reduce the risk of a heart attack.

Using the same technology as the COVID-19 vaccine, the shot, known as mRNA-0184, would be injected directly into the heart, according to the U.K. Daily Mail.

Moderna CEO Stéphane Bancel revealed the program in October, describing it as "science fiction medicine."

"We have now in the clinic a super exciting program where we inject mRNA into people's hearts after a heart attack to grow back new blood vessels to help revascularize the heart," Bancel told Sky News Australia at the time, the Daily Mail reported.

He added, "It's a bit like science fiction medicine, but that's what is really exciting to me."

Moderna began testing mRNA-0184 last week, the Daily Mail reported.

Moderna said in its latest business update that the phase 1B clinical trials are being conducted in patients "with stable heart failure" in order to evaluate the shot's safety and tolerability, as well as the body's reaction to the drug and the effects of different dosage levels and frequency.

According to the Daily Mail, the shot instructs the heart to generate the relaxin hormone, which will improve blood flow and potentially allow new blood vessels to grow after a heart attack.

According to the Moderna website, "mRNA-0184 encodes for relaxin, a naturally occurring hormone that is known to cause hemodynamic changes that are potentially beneficial for heart failure patients."

A heart attack occurs when the heart muscle doesn't get enough blood.

According to the CDC, about a half of all Americans are at risk of a heart attack due to factors that are mostly controllable, including high blood pressure, high blood cholesterol and smoking.

Those who have suffered a heart attack before are also significantly more likely to suffer another in the future.

In fact, around 20 percent of people who have had a heart attack are hospitalized from another within five years, the Daily Mail reported.

The mRNA-0184 vaccine is designed to be injected weeks or even months after a heart attack.

"The mRNA sequence of mRNA-0184 is engineered to instruct the body to produce relaxin with an extended half-life, with the goal of producing a sustained clinical benefit in heart failure patients," Moderna explained.

"This longer half-life may result in more durable effects compared to previous approaches."

The company hopes the drug will "result in more durable effects compared to previous approaches targeting heart failure."

This article appeared originally on The Western Journal.

Written by: Carson Choate, The Western Journal

NATIONAL NEWS

SEE ALL

New Jersey Congressman Donald Payne Jr. Dies at 65 After Health Struggles

New Jersey Congressman Donald Payne Jr. has died at the age of 65 after enduring severe health issues, including a heart attack. Representative Donald Payne…
2 hours ago
 • By Staff Writers

Irsa Hirsi Faces Backlash And Legal Actions Over Protest Incident At Columbia

The recent Columbia University incident involving Irsa Hirsi, Congresswoman Ilhan Omar's daughter, has drawn national attention and controversy. During a pro-Palestine demonstration, Hirsi alleged she…
2 hours ago
 • By Staff Writers

President Joe Biden Critiques Trump at Union Conference, Endorsed for 2024

President Joe Biden delivered pointed remarks at a recent union conference, stirring both laughter and politicized commentary. During his speech, President Biden humorously recalled Trump's…
2 hours ago
 • By Staff Writers

Supreme Court Deliberates on State Abortion Limits in Emergency Medical Cases

Washington's highest judicial body, the U.S. Supreme Court, initiated deliberations on a major legal face-off concerning the provision of emergency abortions under strict state laws.…
2 hours ago
 • By Staff Writers

Juvenile Dolphin Found Shot Dead On Louisiana Beach

A juvenile bottlenose dolphin was discovered dead on a Louisiana beach, sparking a federal investigation. The young dolphin's body was riddled with bullets affecting vital…
4 hours ago
 • By Staff Writers

DON'T WAIT.

We publish the objective news, period. If you want the facts, then sign up below and join our movement for objective news:

    LATEST NEWS

    Newsletter

    Get news from American Digest in your inbox.

      By submitting this form, you are consenting to receive marketing emails from: American Digest, 3000 S. Hulen Street, Ste 124 #1064, Fort Worth, TX, 76109, US, http://americandigest.com. You can revoke your consent to receive emails at any time by using the SafeUnsubscribe® link, found at the bottom of every email. Emails are serviced by Constant Contact.
      Christian News Alerts is a conservative Christian publication. Share our articles to help spread the word.
      © 2024 - CHRISTIAN NEWS ALERTS - ALL RIGHTS RESERVED
      magnifier